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apalutamide will minimize the level or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with medicine which can be CYP3A4 substrates can lead to decrease publicity to these remedies.Modafinil appeared to produce a concentr
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